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Anti-NCAM1 Mouse Monoclonal Antibody (CF594) [clone: NCAM1/795]

Fornitore: Biotium

BNC940795-500 BNC940795-100
BNC940795-500EA 530 EUR
BNC940795-500 BNC940795-100
Anti-NCAM1 Mouse Monoclonal Antibody (CF594) [clone: NCAM1/795]
Anticorpi
This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135 kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.

Type: Primary
Antigen: NCAM1
Clonality: Monoclonal
Clone: NCAM1/795
Conjugation: CF594
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human
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