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Anti-TP53 Mouse Monoclonal Antibody (CF640R) [clone: BP53-12 DO-7]

Fornitore: Biotium
BNC400723-500 BNC400723-100
BNC400723-500EA 560 EUR
BNC400723-500 BNC400723-100
Anti-TP53 Mouse Monoclonal Antibody (CF640R) [clone: BP53-12 DO-7]
Anticorpi
Recognizes a 53 kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p53 under denaturing and non-denaturing conditions. Its epitope maps within the N-terminus (aa 20-25) of p53 oncoprotein. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to MDM2, SV40 T antigen and human papilloma virus E6 protein. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma, lungMore Product Information
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