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Anti-NEFH Mouse Monoclonal Antibody (CF405S) [clone: NF421]

Fornitore: Biotium

BNC040421-500 BNC040421-100
BNC040421-500EA 530 EUR
BNC040421-500 BNC040421-100
Anti-NEFH Mouse Monoclonal Antibody (CF405S) [clone: NF421]
Anticorpi
This MAb reacts with a 200 kDa protein, identified as heavy sub-unit of neurofilaments (NF-H). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.

Type: Primary
Antigen: NEFH
Clonality: Monoclonal
Clone: NF421
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Chicken, Human, Mouse, Pig, Rat
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