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Anti-TGM2 Mouse Monoclonal Antibody (CF488A) [clone: TGM2/419]

Fornitore: Biotium
BNC880419-500 BNC880419-100
BNC880419-500EA 560 EUR
BNC880419-500 BNC880419-100
Anti-TGM2 Mouse Monoclonal Antibody (CF488A) [clone: TGM2/419]
Anticorpi
Recognizes a 77-85 kDa protein, identified as cellular or tissue transglutaminase II (TGase II). Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. TheMore Product Information
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