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Anti-MS4A1 Mouse Monoclonal Antibody (CF594) [clone: 109-3C2]

Fornitore: Biotium
BNC940355-500 BNC940355-100
BNC940355-500EA 560 EUR
BNC940355-500 BNC940355-100
Anti-MS4A1 Mouse Monoclonal Antibody (CF594) [clone: 109-3C2]
Anticorpi
Recognizes a protein of 30-33 kDa, which is identified as CD20 (Workshop V; Code CD20.12. Workshop IV; Code B17). It recognizes an extracellular domain of CD20. It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. The protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B-cells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as calcium channel involved in B cell activation and cell cycle progression.

Type: Primary
Antigen: MS4A1
Clonality: Monoclonal
Clone: 109-3C2
Conjugation: CF594
Epitope:
Host: Mouse
Isotype: IgG3 kappa
Reactivity: Human
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