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Anti-CCND1 Mouse Monoclonal Antibody (Biotin) [clone: DCS-6]

Fornitore: Biotium
BNCB0007-500 BNCB0007-100
BNCB0007-500EA 560 EUR
BNCB0007-500 BNCB0007-100
Anti-CCND1 Mouse Monoclonal Antibody (Biotin) [clone: DCS-6]
Anticorpi
Recognizes a protein of 36 kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). About 40% of breast carcinomas are positive for Cyclin D1. Occasionally, hairyMore Product Information
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Specifiche

Simbolo dell'antigene CCND1
Tipo di anticorpi Cyclin D1
Environmentally Preferable
Tipo anticorpo Primary
Clonalità Monoclonale
Coniugazione Biotina
Clone Clone DCS-6
Reattività Monkey,Human,Rat,Mouse
Ospite Mouse
ID gene 523852 , 667996
Isotipo IgG2a kappa
Western blot Yes
ImmunoChimica Yes
ImmunoFluorescenza Yes
Concentrazione 0,1 mg/ml
Tampone di conservazione PBS/0,1% BSA/0,05% azide

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