Glycitein ≥98%
Fornitore: Cayman Chemical
Synonyms:
7-Hydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one, 7,4'-Dihydroxy-6-methoxyisoflavone
Glycitein is an O-methylated isoflavone that comprises 5 to10% of the total isoflavones in soy food products.
This phytoestrogen is reported to have weak estrogenic activity, displacing estradiol binding at the estrogen receptor in vitro with an IC50 value of 3,94 μM. It suppresses the proliferation of osteoblasts and promotes differentiation from its progenitor.
It has also been used to attenuate proliferation (10 μM) of aortic smooth muscle cells related to atherosclerotic vascular change in stroke-prone hypertensive rats and to protect against beta amyloid (Aβ)-induced toxicity and oxidative stress (100 μg/ml) in C. elegans expressing human Aβ.
Formula:
C₁₆H₁₂O₅ Peso molecolare: 284,27 g/mol Temperatura di stoccaggio: Congelamento |
MDL Number:
MFCD00016679 CAS Number: 40957-83-3 |
Risultati del test di specificazione
Purity | ≥98% |
Formulation | A Crystalline Solid |
λmax | 232, 261, 319 nm |
Smiles | O=C1C(C2=CC=C(O)C=C2)=COC3=CC(O)=C(OC)C=C31 |
InChI Code | 1S/C16H12O5/c1-20-15-6-11-14(7-13(15)18)21-8-12(16(11)19)9-2-4-10(17)5-3-9/h2-8,17-18H,1H3 |
InChI Key | DXYUAIFZCFRPTH-UHFFFAOYSA-N |
Storage | −20 °C |
Shipping | Room temperature in continental US; may vary elsewhere |
Stability | 2 years from the QC date provided on the Certificate of Analysis, when stored properly |
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