6-Aminonicotinamide, pale yellow crystalline powder
Fornitore: MP Biomedicals
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Pericolo
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Synonyms:
6-Aminopyridine-3-carboxamide
6-Aminonicotinamide was found to inhibit NADP+-dependent enzyme, 6-phosphogluconate dehydrogenase.
6-AN interferes with glycolysis, resulting in ATP depletion and synergizes with DNA-crosslinking chemotherapy drugs, like cisplatin, in killing cancer cells (IC50 = 0.5 mM). 6-AN also reduces cardiovascular oxidative injury following ischemia/reperfusion. In addition, 6-AN causes glial neurodegeneration.
Formula:
C₆H₇N₃O Peso molecolare: 137,14 g/mol Temperatura di stoccaggio: Ambiente |
MDL Number:
MFCD00006327 CAS Number: 329-89-5 EINECS: 206-349-7 |
Risultati del test di specificazione
Identity Test | Passes |
FTIR | Conforms to Standard |
Melting Point | 240 - 250 °C |
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