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6-Aminonicotinamide, pale yellow crystalline powder

Fornitore: MP Biomedicals
Pericolo

Synonyms: 6-Aminopyridine-3-carboxamide

0215010305 0215010301
ICNA0215010305EA 531 EUR
ICNA0215010305 ICNA0215010301
6-Aminonicotinamide, pale yellow crystalline powder
6-Aminonicotinamide

6-Aminonicotinamide was found to inhibit NADP+-dependent enzyme, 6-phosphogluconate dehydrogenase.


6-AN interferes with glycolysis, resulting in ATP depletion and synergizes with DNA-crosslinking chemotherapy drugs, like cisplatin, in killing cancer cells (IC50 = 0.5 mM). 6-AN also reduces cardiovascular oxidative injury following ischemia/reperfusion. In addition, 6-AN causes glial neurodegeneration.

Formula: C₆H₇N₃O
Peso molecolare: 137,14 g/mol
Temperatura di stoccaggio: Ambiente
MDL Number: MFCD00006327
CAS Number: 329-89-5
EINECS: 206-349-7

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Risultati del test di specificazione

Identity Test Passes
FTIR Conforms to Standard
Melting Point 240 - 250 °C

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