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Anti-CD59 Mouse Monoclonal Antibody (Purified, BSA-free) [clone: MACIF/629]

Fornitore: Biotium
BNUM0629-50
BNUM0629-50EA 417 EUR
BNUM0629-50
Anti-CD59 Mouse Monoclonal Antibody (Purified, BSA-free) [clone: MACIF/629]
Anticorpi
Reacts with human CD59, a 20 kDa glycosyl phosphatidyl-inositol (GPI)-anchored cell surface protein. CD59 regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. It inhibits formation of MAC, thus protecting cells from complement-mediated lysis. Genetic defects in GPI-More Product Information
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